Scientific Name: Macaca fascicularis
Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Euarchontoglires-> Primates-> Haplorrhini-> Simiiformes-> Catarrhini-> Cercopithecoidea-> Cercopithecidae-> Cercopithecinae
Summary: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015] [NCBI] [Proteinatlas]
Data set information
| Project | Date | Technology | Tissue | Condition | Cell | PMID/DOI |
|---|---|---|---|---|---|---|
| Vthunter_1027 | 2019.11 | 10X Genomics | AorticArtery | Normal | 4383 | Link |
| Vthunter_1028 | 2019.11 | 10X Genomics | CoronaryArtery | Normal | 3606 | Link |
| Vthunter_110069 | 2019.12 | MARS-seq | TotalBrain | Normal | 768 | Link |
Featureplot of receptors
Expression: Broad expression in lung (RPKM 53.0), thyroid (RPKM 21.5) and 19 other tissues?
